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Viral infections may promote neurodegenerative diseases: study

A similar phenomenon occurs in Alzheimer’s and Parkinson’s disease, which also exhibit assemblies of misfolded proteins, according to the researchers Transmission of aggregates could involve direct cell-to-cell contact, the release of “naked” aggregates into extracellular space or packaging in vesicles, which are tiny bubbles surrounded by a lipid envelope that are secreted for communication between cells. “However, viral proteins could also act differently: They could increase intercellular spreading of protein aggregates already ongoing in neurodegenerative diseases like Alzheimer’s,” she added.

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