A study conducted recently has observed that the common drug used for treating and (chest pain) is associated with an increased risk of out-of-hospital sudden Sudden causes around half of the cardiac deaths in and one in five natural deaths. ” The study examined if nifedipine and amlodipine, dihydropyridines widely used for and angina, are linked with out-of-hospital cardiac arrest. The nifedipine doses most often used and studied in this investigation are 30 mg and 60 mg (90 mg is available but infrequently used) and the amlodipine doses are 5 mg and 10 mg. The analysis was done using data from the Dutch Resuscitation Studies registry (ARREST, 2005-2011) and confirmed in the Danish Cardiac Arrest Registry (DANCAR , 2001-2014), both part of ESCAPE-NET. Controls were from the Dutch PHARMO Database Network and the general population in In total, the study included 2,503 patients and 10,543 controls in the ARREST analysis and 8,101 patients and 40,505 controls in the DANCAR analysis.
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